ganglioside|gangliosides in English

noun

any glycolipid found mainly in ganglia (Anatomy)

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1. Among the carbohydrate acceptors tested, $i(N)-acetylneuraminic acid and the gangliosides GD¿3?

2. Presence and isotype of anti-ganglioside antibodies in healthy persons, motor neuron disease, peripheral neuropathy, and other diseases of the nervous system"."

3. Hexosamine estimations in the grey matter of 7 cases of Tay Sachs disease and of 7 cases of other forms of Amaurotic idiocy show that ganglioside accumulation is a

4. Cerebrospinal fluid was investigated in a case of infantile amaurotic idiocy (Tay-Sachs' disease) and in eight “normal” cases as to the occurrence of gangliosides by means of thin layer chromatography.

5. Disclosed are uses of gangliosides GM1 and/or asialo-GM1 and substances simulating the carbohydrate portion of said gangliosides with regard to bonding to anti-GM1 antibodies and/or anti-AGM1 antibodies for producing agents which bind or block anti-GM1 antibodies and/or anti-AGM1 antibodies which bond to natural killer cells (NKC) or for blocking antigen-presenting cells and producing a T-cell anergy, and for producing an affinity material for the extracorporeal removal of anti-GM1 antibodies and/or anti-AGM1 antibodies in order to prevent, inhibit, and treat malignant cancers.

6. ‘The condition differs from the other forms of Amaurotic idiocy by virtue of lack of fundal changes and the presence of significant cerebellar dysfunction.’ ‘Klenk found no increase in the total amount of gangliosides; but Cumings reported an increase in the neuraminic acid level in the cortex in adult cases of Amaurotic family idiocy.’